Opposing pitchers must be sharp when matched up against Dodgers stud Zack Greinke. Rockies right-hander Jordan Lyles was not sharp Saturday night. The result was his first loss of the season.

Lyles walked five in six innings. He also gave up five hits and four earned runs. He was hanging in there until a two-run single by Adrian Gonazalez in the fifth stretched the Los Angeles lead to 4-1.

"Tonight was not good," Lyles said after the game, per MLB.com. "I cannot walk that many people."

His ERA jumped more than a point to 3.50, but he will have a chance to lower it Thursday against San Diego.