Santana allowed three hits and two walks with three strikeouts in three innings during Tuesday's 6-4 win over Cleveland.
Starter Brady Singer left with an arm injury in the first inning, but Santana was able to provide some length out of the bullpen. The 38-year-old hasn't had a great September, posting a 6.75 ERA and 2.36 WHIP in 9.1 innings, so Tuesday was a rare bright spot. He's fared better on the year with a 4.76 ERA, 1.34 WHIP and 51:22 K:BB across 64.1 innings overall, mainly in a multi-inning role.