Lorenzen left his start against Washington on Wednesday as a precaution due to lower-body fatigue.
Lorenzen was activated off the injured list earlier Wednesday after missing the past month with a hamstring strain, so the Royals likely didn't want to push it once he reported discomfort on the mound in the third inning. The 32-year-old's abbreviated outing will presumably mark the end of his regular season, leaving him with a 3.37 ERA and 1.25 WHIP alongside a 94:60 K:BB across 25 appearances (24 starts), and he'll now look to prepare for the Royals' postseason run.