Santiago (1-1) gave up two runs on three hits and a walk while striking out out one over 6.1 innings Tuesday but took the loss as the Twins fell 2-1 to the Tigers.
On an afternoon when offense was at a premium, Santiago made only one mistake, but that was enough as James McCann drilled the first pitch he saw in the fifth inning to left-center field for a two-run homer. Much as he did last season Santiago has gotten off to a good start to 2017, posting a 2.38 ERA through his first two outings, but his 5:3 K:BB in 11.1 innings suggests fantasy GMs shouldn't expect that success to continue. The left-hander's next trip to the mound will come Sunday at home against the White Sox.