Twins pitcher Ricky Nolasco failed to make it out of the fourth inning and was hit with the loss in his first start of the season on Wednesday against the Tigers.

Nolasco surrendered a two-run single to Ian Kinsler and a run-scoring double to Miguel Cabrera in the third inning. He allowed a run-scoring triple to Anthony Gose before he was pulled for Tim Stauffer with no outs in the fourth.

"I put in a lot of hard work and all that, but one start isn't going to kill you as far as mental-wise," Nolasco said. "So I just have to go back to work and do what I have to do for the next one."

The right-hander permitted six runs and six hits in three innings, walked four and struck out two.

"The first couple innings, he came out and did a good job, but lost his command from that point forward," manager Paul Molitor said. "I'm not sure if the cool weather or slick baseballs affected him as the game went on, but obviously, he lost some of the things he had the first couple innings."

Nolasco will try to get back on track Monday at home against Kansas City. He went 2-2 with a 3.31 ERA in five starts against Kansas City in 2014.