Jeffers went 1-for-3 with a solo home run in a 3-1 win over the Indians on Friday.
Jeffers provided some insurance after taking Shane Bieber deep with two outs in the seventh inning to extend the Twins' lead to 3-0. The rookie has homered in two of his last three games but could see a decrease in playing time shortly as Mitch Garver (side) may be activated from the injured list during in the next week.