Vaughn went 1-for-5 with a solo home run in Wednesday's 4-3 extra-innings loss to the Angels.
The first baseman took Jack Kochanowicz deep in the fourth inning to get the White Sox on the board. The blast added to Vaughn's impressive September, and he's batting .345 (19-for-55) on the month with four homers and eight RBI in 14 games. It's been a roller coaster of a season for the 26-year-old, but he now sits one long ball short of his second straight 20-homer campaign.