The White Sox designated Mendick for assignment Wednesday.
Mendick will give up his spot on the 40-man roster and 26-man active roster to third baseman Nick Senzel, whom the White Sox signed to a one-year contract Wednesday. While operating largely as a short-side platoon player in the infield for the White Sox this season, Mendick slashed .197/.243/.318 with three home runs and six stolen bases over 141 plate appearances.