White Sox starter Jose Quintana gave up nine runs and 10 hits in four innings to suffer his first loss of the year.
Quintana gave up two home runs to Yoenis Cespedes, including a grand slam. He walked one and struck out one, while falling to 1-1 on the year with an 8.40 ERA. Quintana threw 56 strikes out of 93 pitches.
"He got ahead early on quite a few guys, he was probably 0-2, 1-2, but just didn't seem to come right after them," White Sox manager Robin Ventura said to ESPN.com. "Come right after them. I think he was picking too much and once we got to a point he probably got too much of the plate.
"It's a tough lineup to go through, but you do have to be a little more aggressive and have them swing the bat," Ventura continued. "He just seemed to be 3-2 on everybody."
Quintana's next start will be Friday against Kansas City and Danny Duffy.