Murakami is absent from the lineup for Wednesday's tilt in Cleveland.
Murakami wore the golden sombrero in Tuesday's loss to the Guardians, and he's 1-for-19 with 12 strikeouts over his last six contests. It's the second time he's been out of the lineup over the White Sox's past three games against left-handed hurlers. Miguel Vargas will slide across the diamond to first base, and Colson Montgomery will play third base in Wednesday's rubber match.