Hopkins (illness) was listed as a non-participant on Wednesday's practice estimate.
At this stage, Hopkins' illness is unlikely to impact his status for Sunday's game against the Titans, but coach Bill O'Brien could still choose to rest or limit the workloads of some of the Texans' key players, with an eye toward protecting them for the postseason. For his part, O'Brien told Aaron Wilson of the Houston Chronicle that the Texans plan to play to win Sunday. Wilson notes that if the Chiefs beat the Chargers in a game that kicks off at 1 p.m. ET, the Texans' playoff seeding can't be affected by the result of the team's regular-season finale, which kicks off at 4:25 p.m. ET.