Bartch suffered a high-ankle sprain in Sunday's win over the Bears and is slated to go on injured reserve this week, Nick Wagoner of ESPN.com reports.
Bartch's season may be over, as a move to IR would force him to miss the 49ers' final four games of the regular season. In that case, San Francisco would have to qualify for a postseason spot for the 26-year-old to take the field again before the 2025 season.