Aiyuk corralled four of six targets for 94 yards in Sunday's 23-7 win over the Texans.
Aiyuk collected 94 of rookie Trey Lance's 249 passing yards, most of which came in the second half of the contest. Deebo Samuel and Elijah Mitchell (knee) were the recipients of Lance's two touchdown throws, but Aiyuk set up both scores with big chunk plays between the 20s. The rookie quarterback was inconsistent at times, but he eventually got the ball into most of his playmakers' hands. Jimmy Garoppolo (thumb) is considered questionable for the team's Week 18 finale against the Rams, but Aiyuk will retain modest fantasy value with either of San Francisco's potential starting quarterbacks.