Kirk (calf) is not suited up for Thursday's preseason opener against the Titans, Nick Wagoner of ESPN.com reports.
Kirk will spend Thursday night's contest out of uniform on the sideline as he continues to deal with the calf injury he sustained in late July. Once healthy, Kirk will look look to solidify his standing in a 49ers' WR corps that also features Mike Evans (quad), Deebo Samuel and De'Zhaun Stribling. The 29-year-old is coming off a 2025 regular season in which he recorded 28 catches (on 52 targets) for 239 yards and one touchdown across 13 games with the Texans.