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Head coach Kyle Shanahan said Monday that McCaffrey is dealing with a mild right calf strain and won't play Sunday against the Rams, Nick Wagoner of ESPN.com reports.

With the 49ers having clinched the No. 1 seed in the NFC, the team has no reason to play McCaffrey in Week 18 at less than 100 percent health. The star running back thus will target a return to action in the divisional round of the playoffs following the 49ers' first-round bye. With McCaffrey not in line to face Los Angeles this weekend, Elijah Mitchell and Jordan Mason are available to handle the team's backfield duties, while Tyrion Davis-Price is a candidate to be promoted from San Francisco's practice squad.

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