Samuel (groin) didn't practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
Given that he's expected to miss 1-to-2 games due to a groin strain, Samuel likely won't practice in any fashion this week before the 49ers rule him out for Sunday's contest at Seattle. In his absence, the 49ers will rely on Brandon Aiyuk, Jauan Jennings, Trent Sherfield and Travis Benjamin at wide receiver, while River Cracraft and Connor Wedington are candidates to be elevated from the practice squad for game day.