Samuel (shoulder) won't practice Wednesday, Cam Inman of The San Jose Mercury News reports.

On the heels of back-to-back 100-yard receiving performances, Samuel has become a go-to option for quarterback Jimmy Garoppolo. It hasn't hurt that George Kittle (knee/ankle) has been sidelined during that stretch, while Emmanuel Sanders played through a rib cartilage injury this past Sunday against the Cardinals. Samuel joined that duo as a non-participant Wednesday, and ensuing practice sessions should help to parse out the pass-catching pecking order.