Samuel (glute) started and caught one of two targets for nine yards in Sunday's 15-10 preseason win over the Chargers.
Samuel was dealing with glute tightness following Friday's joint practice with these same Chargers, but his prompt return to the field should alleviate any concern regarding the injury. Health should be the main focus for the 25-year-old after suffering through multiple lower-body injuries that diminished his 2020 campaign. Expect Samuel to get one more appearance this preseason when the 49ers take on their regional rival in the Raiders on Sunday.