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Mitchell isn't in line to play in Friday's preseason game in Las Vegas, Eric Branch of the San Francisco Chronicle reports.

A strained hamstring sidelined Mitchell for the first two exhibitions, and even though he returned to practice Wednesday, the 49ers will opt to keep him in street clothes two days later. He'll thus turn his focus to Week 1, when he's expected to serve as the primary backup to All-Pro running back Christian McCaffrey (calf). In 27 regular-season games in his three-year career, Mitchell has averaged 4.7 YPC while scoring 10 total touchdowns.

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