Prysock (shoulder) was a full participant at the 49ers' practice Tuesday, Matt Maiocco of NBC Sports Bay Area reports.
Prysock suffered a shoulder injury in the team's preseason finale versus the Raiders on Aug. 27 but he now appears to be back to full health. The 23-year-old is expected to operate as a top reserve option behind Renardo Green (hamstring) and Deommodore Lenoir at cornerback during his rookie campaign.