Kittle (Achilles) said Sunday that he's "very confident" he won't start the season on PUP and that he's still got a chance to play Week 1 versus the Rams, Nick Wagoner of ESPN.com reports.
Kittle is recovering from a torn Achilles suffered on Jan. 11, and he's maintained this offseason that he'll be ready for the Week 1 opener versus the Rams in Melbourne, Australia on Sept. 10. He added that the decision about whether he'll play Week 1 should be made before the 49ers depart for their international game versus the Rams, per Wagoner. The soon-to-be 33-year-old recorded back-to-back 1,000-yard campaigns in 2023 and 2024, but he tallied 628 yards on 57 catches across 11 appearances during the 2025 regular season. When healthy, Kittle should still be a key target for San Francisco quarterback Brock Purdy, especially after wide receiver Ricky Pearsall underwent a season-ending surgery to repair his PCL this August.