Kittle won't practice Thursday due to a hamstring injury, Nick Wagoner of ESPN.com reports.
Kittle wasn't included on the 49ers' initial Week 3 injury report, but he'll be given Thursday off after experiencing tightness in his hamstring coming out of Wednesday's practice session, per Adam Schefter of ESPN. The mid-week absence suddenly threatens Kittle's availability for Sunday's game against the Rams, but the 49ers won't decide whether he'll carry a designation into the weekend until after Friday's practice. With starting wideout Deebo Samuel (calf) already expected to miss Sunday's contest, Kittle's status takes on even greater significance than usual.