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Kittle (hamstring) isn't practicing Friday, Eric Branch of the San Francisco Chronicle reports.

It's a poor sign for his Week 3 availability after Kittle was a mid-week addition to the injury report, as he initially was listed as a non-participant Thursday. Another absence suggests this is more than just caution over minor soreness or tightness, likely setting Kittle up for a game designation on the final injury report ahead of Sunday's matchup with the Rams.

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