Kittle (calf) isn't practicing Wednesday, Matt Maiocco of NBC Sports Bay Area reports.
Kittle drew 11 targets and played 92 percent of the 49ers' offensive snaps in the Week 4 loss to Seattle, but he apparently aggravated the calf injury that rendered him questionable heading into the game. He's now considered day-to-day, with the Niners hoping their star tight end can continue to play through the injury this weekend against the division-leading Cardinals.