Coach Kyle Shanahan said Kittle (hamstring) won't practice Wednesday, Nick Wagoner of ESPN.com reports.
Shanahan relayed Monday that Kittle was dealing with hamstring irritation, which will keep him out of the first session of the week. Kittle has gutted through hamstring, rib and foot injuries this season, missing only one game (Week 3) as a result, but it's unclear if he may be in danger of another DNP in Week 11. His activity level, or lack thereof, Thursday and Friday likely will provide some insight into his odds to play Sunday against the Seahawks.