San Francisco head coach Kyle Shanahan said Monday that Hargrave is dealing with a partially torn right tricep and will likely miss the rest of the season, Nick Wagoner of ESPN.com reports.

Hargrave sustained the injury in Sunday's 27-24 loss to the Rams, and though the team was initially optimistic that the issue was a minor one, further testing revealed a more serious concern that will likely require season-ending surgery. In the second season of a four-year, $84 million deal, Hargrave will represent a major loss for the San Francisco defensive front. After logging 44 tackles and seven sacks in his first season with the 49ers in 2023, Hargrave will end his 2024 campaign with seven stops (four solo) and one sack over three contests.