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Brown (ankle) was a non-participant in Thursday's practice, Nick Wagoner of ESPN.com reports.

Brown was limited in Wednesday's session, so this is a downgrade for San Francisco's safety headed into Sunday's Week 18 finale against the Cardinals. The Niners have a laundry list of injuries on the defensive side of the ball and could be playing a number of backups in a game that has little meaning for either club.

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