Coach Kyle Shanahan said he expects Garoppolo (ankle) to be a full practice participant Wednesday, Nick Wagoner of ESPN.com reports.
Garoppolo returned to action in last Sunday's loss to the Dolphins for the first time since Week 2, but his high right ankle sprain didn't allow him to finish the contest. When Garoppolo stepped aside at halftime, Shanahan noted he wanted to "protect" the quarterback, which may have been cover for his brutal performance to that point in the game (7-for-17 passing for 77 yards and two interceptions). Assuming he practices in full Wednesday and maintains said status through the end of the week, Garoppolo will have his hands full this weekend versus the Rams' second-ranked pass defense.