Goodwin (thigh/hamstring) isn't practicing Wednesday, Matt Maiocco of NBC Sports Bay Area reports.
Goodwin has been dealing with a deep thigh bruise since Week 1, drawing just nine targets in three games while failing to reach his anticipated snap counts. He apparently picked up the hamstring injury in Sunday's 29-27 loss to the Chargers, providing yet another concern amidst a massively disappointing season. Even if he does make his way back to full strength, Goodwin will have to work with C.J. Beathard at quarterback instead of Jimmy Garoppolo (knee). The 49ers have a slew of injury concerns as they prepare to host the Cardinals in Week 5.