Hufanga (knee) was listed as a full participant in Wednesday's practice session, Jenna Laine of ESPN.com reports.
Wednesday's practice was Hufanga's first as a full participant this season, perhaps setting the stage for him to make his 2024 debut Sunday versus the Rams. Before suffering a season-ending ACL tear last November, Hufanga tallied 52 tackles (39 solo) and three interceptions. If available against the Rams, Hufanga will likely reclaim a starting role at safety, though the 49ers could ease him back into the mix with a more limited snap count than usual.