Sherfield caught one of two targets for 12 yards in Sunday's 23-7 win over Houston.
Sherfield was on the field for eight offensive snaps (13 percent), which is in line with the amount of playing time he has been receiving at No. 4 on the depth chart. The 25-year-old got his first catch and multi-target game since Week 13, and it was no coincidence that Trey Lance was under center. The two players showed some rapport during the preseason, when they connected on two long plays from scrimmage. It's unclear whether Lance will get another start or if Jimmy Garoppolo (thumb) will heal before next week's tilt against the Rams, but Sherfield won't see enough playing time to make a fantasy impact, even if one quarterback prefers him over the other.