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Lance (ankle) won't return to Sunday's game against the Seahawks.

Lance injured his ankle on a run-pass option at the end of a two-yard carry, when his right leg was bent back on a tackle by Seattle linebacker Cody Barton. As Lance was taken off the field on a cart, his right ankle was donning an air cast, per Chris Biderman of The Sacramento Bee. While the severity of the concern currently is unknown, Lance will hand over the keys to the 49ers offense to Jimmy Garoppolo.

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