Higgins (ankle) doesn't appear to be practicing Wednesday, Ben Baby of ESPN.com reports.
Higgins is coming off consecutive weeks with 100-plus receiving yards and a touchdown, despite dealing with cramping in the first game and an ankle injury late in the second one. A report issued after Sunday's loss to the Chargers suggested Higgins wasn't expected to miss time, but his absence from practice Wednesday means fantasy managers will need to keep tabs on the situation ahead of this weekend's game against the 49ers.