Coach Sean McDermott relayed Friday that Samuel (pectoral) may be out "more than one week," but McDermott doesn't believe Samuel will go on injured reserve, Alaina Getzenberg of ESPN.com reports.
Samuel has already been ruled out for Sunday's game in Seattle, and it sounds like he's far from a lock to return Sunday, Nov. 3 against the Dolphins in Week 9. He's unlikely to play a significant role even when healthy, as Samuel has exceeded 22 receiving yards only once for a Bills passing game that likely will have even fewer targets to go around after trading for Amari Cooper last Tuesday.