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Samuel is week-to-week due to turf toe, Maddy Glab of the Bills' official site and Adam Schefter of ESPN report.
Meanwhile, Marquez Valdes-Scantling (neck) could miss multiple weeks, so the Bills' WR depth is being challenged ahead of Week 1. For now, the team's top options at the position are Khalil Shakir and Keon Coleman, with Mack Hollins and KJ Hamler candidates to see added reps for any length of time Samuel is sidelined.
