The Bills signed Pettis to a contract Thursday.
The 2018 second-rounder has played in 66 career games, racking up 92 catches for 1,231 yards and 13 touchdowns. He participated in eight regular-season contests for the Saints in 2025, collecting nine receptions for 127 yards, but he was primarily a special-teams player. The release of Jalen Virgil (undisclosed) enabled Pettis to earn a roster spot for training camp.