Knox caught one of two targets for 23 yards in Sunday's 34-28 win over the Cardinals.
Knox operated as the No. 2 tight end behind Dalton Kincaid, but both tight ends finished the day with just two targets. The 27-year-old Knox was on the field for 58 percent of the Bills' offensive snaps, while Kincaid finished with a 84 percent snap share in the contest. The veteran will likely face an uphill battle for meaningful targets this season, keeping him off the fantasy radar heading into a Week 2 matchup against the Dolphins.