Enemkpali was officially diagnosed with a torn ACL and will miss the 2016 season, Ian Rapoport of NFL.com reports.
Enemkpali suffered the injury during Saturday's preseason opener versus the Colts and will now be the latest Bills' defensive player to suffer a significant injury. He's been ruled out for the rest of the season, meaning Lorenzo Alexander could see an uptick in reps, while Manny Lawson (pectoral) is also expected to see increased playing time once back from injury.