The Bills elevated Brown from the practice squad ahead of Sunday's game against the Patriots.
Brown will be elevated from Buffalo's practice squad for the third time this season with wideouts Jake Kumerow (ankle) and Jamison Crowder (ankle) both still on IR. The 32-year-old Brown logged one target over 15 offensive snaps across his previous two appearances this season, so it's unlikely he'll see a significant workload unless Buffalo opts to rest top wideouts Stefon Diggs, Gabe Davis and/or Isaiah McKenzie during the second half of this Week 18 contest, perhaps unlikely with the Bills playing for the No. 2 seed, unless the game starts to get out of hand.