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Settle (calf) is out Monday against the Titans, Chris Brown of the Bills' official site reports.
Settle logged a limited practice Saturday, but the five-year-pro still isn't ready to take the field. With Ed Oliver (ankle) also ruled out, the middle of the Bills' defensive line will be thinner than you would hope for against Derrick Henry. Settle will work to be ready for Week 3 against the Dolphins.
