McGuire did not participate in Wednesday's practice due to an illness, Mary Kay Cabot of The Cleveland Plain Dealer reports.
McGuire is under the weather to start Week 10 prep, but he'll have two more opportunities to return to practice ahead of Sunday's game against the Jets. The third-year defensive end has logged 16 tackles (10 solo), including 1.0 sacks, and one forced fumble through eight regular-season games.