Hopkins (hamstring) wasn't on the field for the open portion of Friday's practice, Darren Urban of the Cardinals' official site reports.
Hopkins looks destined to go down as a non-participant on the Cardinals' Week 9 practice report for the third day in a row, as does quarterback Kyler Murray (ankle). Head coach Kliff Kingsbury has previously said that Murray doesn't necessarily need to practice this week to suit up Sunday in San Francisco, and the same could apply for Hopkins, who has a history of suiting up in games with little or no practice reps beforehand. The Cardinals' final practice report will be revealed later Friday and will indicate whether Hopkins will carry a designation into the contest or be ruled out ahead of the contest. If he's listed as questionable, Hopkins' status could come down to a game-time decision ahead of Sunday's 4:25 p.m. ET kickoff.