Hopkins wasn't present at the portion of Wednesday's practice open to the media, Darren Urban of the Cardinals' official site reports.
Last week, Hopkins was listed as a non-participant Wednesday due to a non-injury reason. He then remained absent from practice Thursday with neck and back issues before capping the week with a limited session Friday. He proceeded to suit up in Sunday's win over the Giants and put together a bounce-back performance, notching his first 100-yard effort in four games. It'll be interesting to see if Hopkins is dealing with similar or new health concerns, or whether his absence to begin Week 15 was maintenance-related.