Hopkins (hamstring) has been ruled out for Sunday's game in Seattle, James Palmer of NFL Network reports.
Hopkins still hasn't practiced since Week 7 or played in a game since Week 8. With a bye coming up in Week 12, the Cardinals will hope to get their star wideout back in the lineup for a Week 13 contest in Chicago on Dec. 5. Meanwhile, QB Kyler Murray (ankle) appears headed for another game-time decision Sunday afternoon in Seattle.