The Cardinals placed Ledbetter (knee) on injured reserve Friday.
Ledbetter suffered a season-ending knee injury in last week's loss to the Bears and will finish the year on the injured list. 2023 was Ledbetter's first season as a full-time starter, as he started all 12 games he appeared in after starting just four games across his first three seasons. Ledbetter finishes the year with a career-high 46 tackles (21 solo), including 1.5 sacks.