Edwards didn't practice Wednesday due to an ankle injury.
Edwards' absence from practice comes as a surprise, considering that he wasn't known to be contending with an injury coming out of the Chargers' Week 4 loss to the Chiefs before the team went on bye for Week 5. He'll still have two more opportunities to increase his activity in practice, but if Edwards ends up missing this Sunday's game in Denver, Hassan Haskins and Kimani Vidal would be candidates to see complementary work behind top back J.K. Dobbins.