Guyton didn't catch his lone target but rushed once for three yards in Sunday's 30-24 win over the Chiefs.
Guyton handled 41 offensive snaps (62 percent) but couldn't beat out Mike Williams, Keenan Allen and Austin Ekeler for a piece of the target pie. The 24-year-old has deep-threat appeal and could be used on gadget plays, but he's not a dependable fantasy option.