Lissemore was placed on injured reserve Monday after suffering a shoulder injury, Tom Krasovic of the San Diego Union-Tribune reports.
Lissemore was looking to rebound from a poor 2015 in which he managed to play in just 11 games, tallying 16 tackles. While the 28-year-old was not expected to start this season, the injury will tax the Chargers' depth along the defensive line, forcing unheralded players such as Ryan Carrethers or Chuka Ndulue to receive additional snaps on the defensive front.