Mahomes completed 19 of 29 passes for 245 yards, one touchdown and one interception in Sunday's 17-10 win over the Chargers.
Mahomes showed impressive efficiency by averaging 8.5 yards per attempt, though it didn't lead to a strong fantasy showing. The latter is understandable given that the Chiefs lost another key pass catcher after Rashee Rice (knee) went down, leaving Travis Kelce and rookie Xavier Worthy as Mahomes' top two targets. The highlight of his performance came late in the second quarter when he found Worthy for a 54-yard touchdown. With Rice and Hollywood Brown (shoulder) both sidelined for the long term, it may be difficult for Mahomes to turn in his typical fantasy performances on a regular basis.