Kelce (knee), who is listed as questionable, is expected to sit out Thursday's game against the Lions, Ian Rapoport of NFL Network reports.
Per the report, the tight end still may test out his injured knee in a pregame workout, but his official status will be confirmed either way about 90 minutes prior to Thursday's 8:20 p.m. ET starting time. If Kelce ends up inactive for the Week 1 contest, his next chance to play will arrive Sunday, Sept. 17 against the Jaguars.